The occurrence of rabies virus in the lungs, kidneys, bladder, and other tissues of naturally infected cat

Abstract

Isolations of rabies virus from brain, lungs, tongue, bladder, kidneys, sub-maxillar and parotid glands of naturally-infected domestic cat were introduced as intracerebral inoculations in five-day old mice. The samples of virus isolated from the cat tissues were identified as rabies virus by presence of Negri bodies into the cytoplasm of nerve cells of the inoculated mice and by evidence of serum neutralization in samples isolated from the brain and lung. The quantity of virus in the cat tissues was measured by titration tests with lactating mice. The tissues with greater virus content were the sub-maxillary glands, with a titer of 10^-4,0, and the tongue with a titer of 10^-8,5. The brain, parotid glands, lungs and kidneys gave lower titers.